
Rich, velvety cheese pairs with wilted spinach and tender artichokes to coat juicy chicken breasts in this filling twist on a fan-favorite appetizer. This satisfying dish turns a popular dip into a complete dinner, giving you all those crave-worthy tastes while adding lean meat and nutritious veggies. Every mouthful delivers the perfect mix of gooey cheese, soft artichokes, and garden-fresh spinach.
The first time I made this for my cheese-obsessed nephew, he couldn't tell it was healthier. The magic happens when you mix protein-loaded Greek yogurt with cottage cheese, creating amazing creaminess while keeping things lighter than old-school recipes.
Key Ingredients and Smart Shopping Advice
- Chicken Breasts: Pick pieces that are about the same size so they cook evenly. Cutting larger breasts butterfly-style helps them cook through and gives more room for sauce coverage.
- Neufchâtel Cheese: This slimmer cream cheese option adds richness without extra fat. Go for blocks with few added ingredients for the smoothest melting.
- Greek Yogurt: Choose whole-milk Greek yogurt for the smoothest texture that won't break apart while cooking.
- Artichoke Hearts: Go with water-packed instead of marinated ones for better taste control. Tear them by hand instead of cutting to avoid mushiness and add nice texture.

Step-by-Step Cooking Guide
- Chicken Preparation:
- Let chicken breasts come to room temperature first. Dry them thoroughly for better browning, then quickly sear in olive oil until just white outside but still raw inside. Set aside on a plate while you make the sauce.
- Cheese Sauce Creation:
- Put Neufchâtel cheese, Greek yogurt, and cottage cheese in a bowl. Stir until completely smooth, then mix in half your mozzarella, Parmesan, and seasonings.
- Vegetable Integration:
- Carefully fold torn artichoke pieces and spinach into the mixture. Add spinach bit by bit to avoid clumps.
- Assembly Process:
- Cover partly-cooked chicken with cheese mixture and place in a baking dish. Sprinkle remaining cheese on top and bake at 400°F until golden and bubbling.
As someone who loves prepping meals ahead, I've found that making this dish the night before actually makes it taste better, giving all the flavors time to mix together perfectly.
Smart Cooking Tricks
- Keep some artichoke chunks bigger than others for interesting texture differences.
- Let the dish sit for exactly 5 minutes after baking for the best cheese pulls.
- Add fresh herbs just before serving for pretty presentation and bright flavor.
This chicken bake with spinach and artichokes hits the sweet spot between tasty comfort food and healthy eating. Using protein-packed ingredients doesn't mean you'll miss out on flavor or creaminess, making this a great choice for family dinners or weekly meal planning.

Frequently Asked Questions
- → Can I swap fresh spinach for frozen?
- You can definitely use about 8 ounces of frozen spinach instead. Just remember to thaw it completely and squeeze out all the extra water before adding it to your dish.
- → What's a good replacement for Neufchâtel cheese?
- Standard cream cheese makes a perfect swap for Neufchâtel cheese, but keep in mind your dish will be a bit more decadent.
- → Is it possible to make this ahead?
- You can put everything together up to a day before and keep it covered in your fridge. Just add a few more minutes to your baking time when cooking from cold.
- → Why did my dish come out runny?
- Be sure to drain those artichoke hearts properly and really wring out frozen spinach if you're using it. This stops extra liquid from making your dish too wet.
- → How can I tell if the chicken is done?
- Grab a meat thermometer and check that your chicken hits 165°F (74°C). The meat should be white all the way through with no pink spots anywhere.